Recent Publications (March 2010)

Photoinduced Modification of Biomolecules:

Mohler, D. L.; Downs, J. R.; Coonce, J. G.; Mirandi, J. L.; Riera, L.; Reira, V.; Pιrez, J. “Dual Mechanisms of DNA Damage by MoX(h3-allyl)(CO)2(phen) Complexes J. Org. Chem. 2007, 72, 8755-8759.

Maddox, M. P. III; Colton, C. M., Patterson, M. J.; Mohler, D. L. “Dissociation of DNA-Histone Assemblies Resulting from Protein Side-Chain FunctionalizationJ. Am. Chem. Soc. 2007, 129, 11328-11329.

Shell, T. A.; Glass, J., Mackey, M. A.; Layman, K. A.; Mohler, D. L., “Formal DNA Hydrolysis by Mono- and Dinuclear Iron Complexes” Inorg. Chem. 2007, 46, 8120-8122.

Shell, T. A.; Mohler, D. L., “Hydrolytic DNA cleavage by non-lanthanide metal complexesCurr. Org. Chem., 2007, 11, 1525-1542.

Shell, T. A.; Mohler, D. L., "Selective targeting of DNA for cleavage within DNA-histone assemblies by a spermine-[CpW(CO)3Ph]2 conjugate," Org. Biomol. Chem. 2005, 3, 3091.

Cover article: Mohler, D. L.; Downs, J. R.; Hurley-Predecki, A. L.; Sallman, J. R.; Gannett, P. M.; Shi, X. "DNA Cleavage by the Photolysis of Cyclopentadienyl Metal Complexes: Mechanistic Studies and Sequence Selectivity of Strand Scission by CpW(CO)3CH3," J. Org. Chem. 2005, 70, 9093-9102. (supporting information)

Shell, T. A.; Mohler, D. L., "The hydrogen peroxide induced enhancement of DNA cleavage in the ambient light photolysis of CpFe(CO)2Ph: a potential strategy for targeting cancer cells," Bioorg. Med. Chem. Lett. 2005, 15, 4585. (supporting information)

Mohler, D. L.; Coonce, J. G.; Predecki, D., "Photoinduced DNA Cleavage by Benzenediradical Equivalents: 1,3- and 1,4-Bis(dicarbonylcyclopentadienyliron)benzene," Bioorg. Med. Chem. Lett. 2003, 13, 1377-1379.

Mohler, D. L.; Barnhardt, E. K.; Hurley, A. L., "Relative Efficiencies of CpM(CO)nCH3 and CpM(CO)nPh (M = Cr, Mo, W, and Fe) Complexes in Photoinduced DNA Cleavage," J. Org. Chem. 2002, 67, 4982-4984. (supporting information)

Hurley, A. L.; Maddox, M. P., III; Scott, T. L.; Flood, M. R.; Mohler, D. L., "Photoinduced DNA Cleavage by Cyclopentadienyl Metal Complexes Conjugated to DNA Recognition Elements," Org. Lett.2001, 3, 2761.
(supporting information)

Hurley, A. L., Mohler, D. L., "Organometallic Photonucleases: Synthesis and DNA-Cleavage Studies of Cylopentadienyl Metal-Substituted Dendrimers Designed to Increase Double-Strand Scission," Org. Lett. 2000, 2, 2745. (supporting information)

Mohler, D. L.; Dain, D. R.; Kerekes, A. D.; Nadler, W. R.; Scott, T. L., "Organometallic Photonucleases: A Novel Class of DNA-cleaving Agents," Bioorg. Med. Chem. Lett. 1998, 8, 871


Chen, D.; De, R.; Mohler, D. L., “A facile synthesis of thioalkyl- and di(thioalkyl)-substituted bipyridines,” Synthesis, 2009, 211-216.

Huang, J.; Stockwell, D.; Huang, Z.; Mohler,  D. L.; Lian, T. “Photoinduced Ultrafast Electron Transfer from CdSe Quantum Dots to Re-bipyridyl ComplexesJ. Am. Chem. Soc. 2008130,  5632-5633.

She, C.; Guo, J.; Irle, S.; Morokuma, K.; Mohler, D. L.; Zabri, H.; Odobel, F.; Youm, K.-T.; Liu, F.; Hupp, J. T.; Lian, T., "Comparison of Interfacial Electron Transfer through Carboxylate and Phosphonate Anchoring Groups, " J. Phys. Chem. A 2007, 111, 6832-6842.

She, C.; Anderson, N. A.; Guo, J.; Liu, F.; Goh, W-H.; Chen, D.; Mohler, D. L.; Tian, Z.-Q.; Hupp, J. T.; Lian, T., “pH-Dependent Electron Transfer from Molecules to Metal Oxide Nanocrystalline Thin Films," J. Phys. Chem. B, 2005, 109, 19345-19355. (supporting information)

Anderson, N.A.; Ai, X.; Chen, D.; Mohler, D.L.; Lian, T., "Bridge-Assisted Ultrafast Interfacial Electron Transfer to Nanocrystalline SnO2 Thin Films," J. Phys. Chem. B 2003, 107, 14231-14239. (supporting information)

Mohler, D. L.; Chen, D.; Reddy, V. B., "A Facile Synthesis of Homologous 4,4'-Dialkanoic Acid Substituted 2,2'-Bipyridines," Synthesis 2002, 745. (Because of the publisher's copyright, we cannot post the pdf file on the web. Please email for it!)

Janini, T.; Mohler, D. L.; Fattore, J. L., "Rapid Assembly of Rigid Rods by Metal Complexation of Bis(terpyridyl) Ligands," J. Organometal. Chem. 1999, 578, 260.


Mohler, D. L.; Shen, G., “The Synthesis of Tethered Ligand Dimers for PPARg-RXR Protein HeterodimersOrg. Biomol. Chem. 2006, 4, 2082-2087.

Mohler, D. L.; Shen, G.; Dotse, A. K., "Solution and Solid Phase Synthesis of Peptide-Substituted Thiazolidinediones as Potential PPAR Ligands," Bioorg. Med. Chem. Lett. 2000, 10, 2239.